NCT01138943

Chlorhexidine Mouthrinses and Plaque Control

Chlorhexidine Alcohol Base Mouthrinse Versus Chlorhexidine Formaldehyde Base Mouthrinse Efficacy on Plaque Control: Double Blind, Randomized Clinical Trials

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Hôpital Militaire De Rabat · Academic / Other
• Sex: All
• Age: 20 Years – 25 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).

Detailed description

Chlorhexidine (CLX) mouthrinse has been the gold standard as antiplaque solution.However, if its efficiency seems to be preserved even if the chlorhexidine concentration is bellow 0.10%, the formulation of the final product may affect the effectiveness. Thus, it can be concluded from this study that 0.12% CLX alcohol base mouthrinse is significantly more effective in inhibiting plaque than the diluted 0.1% CLX non-alcohol base containing formaldehyde mouthrinse.

Conditions

• Dental Plaque

Interventions

Type	Name	Description
DRUG	Synthodont	15 ml, tree times/day for 07 days Arm: Chlorhexidine alcohol-base mouthrinse
DRUG	Soludent	15ml of 01% Chlorhexidine non alcohol-based, 3 times a day for 7 days Arm: Experimental: non alcohol chlorhexidine mouthrinse

Timeline

• Start date: 2007-02-01
• Primary completion: 2007-03-01
• Completion: 2007-04-01
• First posted: 2010-06-08
• Last updated: 2011-05-16

Locations

1 site across 1 country: Morocco