NCT01133964

Dairy Proteins and Postprandial Appetite Regulation and Energy Expenditure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to examine the effect of dairy proteins (whey and casein) on postprandial appetite regulation and energy expenditure.

Detailed description

Several studies have shown that a high protein intake is associated with a increased loss of body weight and body fat as compared to a diet with a normal or low protein content. The effect seems to be due to a higher diet induced thermogenesis and increase satiety. Milk has a high content of proteins. It contains two very different types of protein: whey and casein. Whey is a soluble protein whereas casein clots into the stomach, which delays its gastric emptying and thus probably results in a slower release of amino acids. It is therefore very likely that the two types of protein affect the thermogenesis and appetite regulation differently. The aim of the present study is to examine the effect of dairy proteins (whey and casein) on postprandial energy expenditure, substrate oxidation and appetite regulation. The study will have a cross-over design including four meals each including a test drink (milk, casein drink, whey drink or water).

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	dairy proteins	Protein drinks with 3.5% protein. The protein source will be whey, casein or whey and casein (20:80; normal content in the milk). In the arm with water no protein will be added.

Timeline

• Start date: 2008-10-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2010-05-31
• Last updated: 2011-06-27

Locations

1 site across 1 country: Denmark