NCT01131468

Prevention of Drug Induced Ototoxicity in Peritoneal Dialysis Patients by N-Acetylcysteine

The Evaluation of the Protective Effect of N-Acetylcysteine Against Drug Induced Ototoxicity in Peritoneal Dialysis Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: TC Erciyes University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether N-acetylcysteine is effective in the prevention of hearing loss in both ears due to aminoglycoside and/or vancomycine induced ototoxicity in peritoneal dialysis patients.

Conditions

• Drug-induced Ototoxicity in Peritoneal Dialysis Patients

Interventions

Type	Name	Description
DRUG	N-acetylcysteine	N-acetylcysteine 600 mg twice daily or vancomycine+amikacin alone

Timeline

• Start date: 2008-02-01
• Primary completion: 2010-04-01
• Completion: 2010-05-01
• First posted: 2010-05-27
• Last updated: 2010-05-27

Locations

1 site across 1 country: Turkey (Türkiye)