NCT01127880

Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax

The Role of Antibiotics in the Reduction of Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax: A Prospective, Double-Blinded Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: St. Luke's Hospital, Pennsylvania · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.

Detailed description

In this study, the medication (an antibiotic which is used to treat or prevent infections) will be compared with a placebo. A placebo is something that looks like a "real" medication, but it doesn't contain any active medication. As a participant in this study, you may receive the active medication (Cefazolin Sodium Injection or Clindamycin) or you may receive a placebo.

Conditions

• Hemopneumothorax
• Pneumothorax

Interventions

Type	Name	Description
DRUG	Ancef or Clindamycin	1 gm of Ancef or 300 mg Clindamycin for those who are penicillin allergic
DRUG	Placebo	.9% Normal Saline as a placebo

Timeline

• Start date: 2005-07-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2010-05-21
• Last updated: 2010-05-21

Locations

1 site across 1 country: United States