Clinical Trials Directory

Trials / Completed

CompletedNCT01126190

Neugranin in Breast Cancer Participants Receiving Doxorubicin/Docetaxel

A Randomized, Double-Blind, Active Comparator, Non-Inferiority Study of Subcutaneously Administered Neugranin (Recombinant Human Albumin-Human Granulocyte Colony Stimulating Factor) or Pegfilgrastim in Subjects With Breast Cancer Receiving Myelosuppressive Chemotherapy (Doxorubicin/Docetaxel), Followed by a Single-Arm, Open-Label Phase of Subcutaneously Administered Neugranin

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
381 (actual)
Sponsor
Teva Branded Pharmaceutical Products R&D, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Determination of the effect of neugranin on the duration and severity of severe neutropenia in participants receiving doxorubicin in combination with docetaxel.

Conditions

Interventions

TypeNameDescription
BIOLOGICALNeugraninNeugranin will be administered per dose and schedule specified in the arm description.
BIOLOGICALPegfilgrastimPegfilgrastim will be administered per dose and schedule specified in the arm description.
DRUGChemotherapyThe chemotherapy regimen for this trial consists of doxorubicin 60 mg/m\^2 and docetaxel 75 mg/m\^2 in combination

Timeline

Start date
2010-06-30
Primary completion
2012-02-29
Completion
2012-02-29
First posted
2010-05-19
Last updated
2023-03-28
Results posted
2023-03-28

Locations

59 sites across 5 countries: Bulgaria, Romania, Russia, Serbia, Ukraine

Source: ClinicalTrials.gov record NCT01126190. Inclusion in this directory is not an endorsement.