Clinical Trials Directory

Trials / Completed

CompletedNCT01123070

TL011 in Severe, Active Rheumatoid Arthritis Patients

A Phase Ib Study Evaluating Safety, Pharmacokinetic and Pharmacodynamic Profiles of a Single Course of TL011 Infusions in Subjects With Severe, Active Rheumatoid Arthritis

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
54 (actual)
Sponsor
Teva Pharmaceutical Industries, Ltd. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the safety and pharmacology of TL011 in patients with severe rheumatoid arthritis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALTL011, anti CD20, for the treatment of rheumatoid arthritisTL011 administered by 2 infusions, 2 weeks apart
BIOLOGICALMabThera infusionsMabThera, administered by 2 infusions, 2 weeks apart

Timeline

Start date
2010-02-05
Primary completion
2012-04-23
Completion
2012-04-23
First posted
2010-05-14
Last updated
2021-10-04
Results posted
2021-10-04

Locations

18 sites across 5 countries: Czechia, Hungary, Italy, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01123070. Inclusion in this directory is not an endorsement.

TL011 in Severe, Active Rheumatoid Arthritis Patients (NCT01123070) · Clinical Trials Directory