Trials / Completed
CompletedNCT01122797
Influence of Adiponutrin in Chronic Liver Disease
Study of Metabolism Influence in Human Alcoholic Liver Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 658 (actual)
- Sponsor
- Erasme University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Increasing evidence attests the influence of multiple metabolic genetic risk factors in the progression of alcoholic liver disease. Deleterious pathways involved in metabolism such as lipid peroxidation and cytokines have been implicated in promoting inflammation leading to fibrosis increase and liver injury progression. The aim of this study was to assess the role of rs738409 single nucleotide polymorphism in the PNPLA3 gene in alcoholic liver disease patients.
Conditions
Timeline
- Start date
- 2003-01-01
- Primary completion
- 2010-01-01
- Completion
- 2010-03-01
- First posted
- 2010-05-13
- Last updated
- 2010-05-13
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT01122797. Inclusion in this directory is not an endorsement.