NCT01122537

Characterization and Differential Diagnosis of Postneurosurgical Meningitis

Clinical Features, Microbiological Characteristics, and Differential Diagnosis of Postneurosurgical Meningitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 78 (actual)
• Sponsor: Asan Medical Center · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

Meningitis is a rare complication following neurosurgical procedures and is associated with high morbidity and mortality. The aim of this study is to describe the clinical characteristics and microbiological characteristics in patients who develope meningitis following neurosurgical operations, and investigate the useful tips for the differential diagnosis of postneurosurgical meningitis.

Detailed description

Besides description of characteristics of patients with postneurosurgical patients, we also will investigate the usefulness of prolonged cerebrospinal fluid (CSF) culture, and profiles of blood and CSF inflammatory markers for the differential diagnosis of meningitis. CSF culture will be extended upto 2 weeks. Serum procalcitonin and C-reactive protein, CSF adenosine deaminase levels will be monitored and analyzed for the differential diagnosis of meningitis.

Conditions

• Neurosurgery

Timeline

• Start date: 2010-05-01
• Primary completion: 2013-09-01
• Completion: 2013-09-01
• First posted: 2010-05-13
• Last updated: 2013-10-01

Locations

1 site across 1 country: South Korea