NCT01120860

Magnetic Resonance Imaging (MRI) and Decline of Aging Aviator Performance

MRI and Decline of Aging Aviator Performance

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 67 (actual)
• Sponsor: Palo Alto Veterans Institute for Research · Academic / Other
• Sex: All
• Age: 45 Years – 100 Years
• Healthy volunteers: Accepted

Summary

The primary purpose of this study is to apply state-of-the-art Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopic Imaging (MRSI) techniques to measure changes over time in the brain.

Detailed description

We expect that MRI and MRSI techniques will be a useful adjunct in research efforts to understand individual differences in performance of a complex attention-demanding task, such as flying a plane or driving a car. Other predictors of change in performance of a complex task may include simple tests of processing speed and working memory, past training and recent practice of the task, and genetic risk factors for degenerative brain disease. In this project, we will examine whether baseline MR measures are as useful as longitudinal MR measures in predicting amount of change over time in task performance. This research is part of a long-term effort to achieve earlier identification of individuals at risk of decline and ultimately minimize loss of function.

Conditions

• Age-related Cognitive Decline

Interventions

Type	Name	Description
DEVICE	MRI	MRI - routine imaging sequences, designed for anatomical quantification

Timeline

• Start date: 2002-11-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2010-05-11
• Last updated: 2017-02-28

Locations

1 site across 1 country: United States