NCT01119989

Effects of an Amino-acid Supplement on Hepatic Lipid Metabolism

Effects of a Supplementation With Amino-acids on Hepatic Lipid Metabolism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: University of Lausanne · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

10 healthy male volunteers will be studied after * a 6 day weight maintenance, balanced diet * a 6 days weight maintenance, balanced diet supplemented with 3 grams fructose/kg body weight/day * a 6 days weight maintenance, balanced diet supplemented with 3 grams fructose/kg body weight/day and 20g amino-acids per day At the end of each 6 days period, the following measurements will be obtained * intrahepatic lipids (1H-MRS) * metabolic effects of fructose ingestion (measurement of substrate oxidation, gluconeogenesis from fructose, palmitate synthesis from fructose, plasma VLDL-kinetics) This is a randomized, double blinded study

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fructose+maltodextrin placebo
DIETARY_SUPPLEMENT	amino-acid + fructose

Timeline

• Start date: 2010-05-01
• Primary completion: 2011-03-01
• Completion: 2011-12-01
• First posted: 2010-05-10
• Last updated: 2018-05-04

Locations

1 site across 1 country: Switzerland