NCT01119690

Hämeenlinna Metabolic Syndrome Research Program: Effects of Rapeseed Oil on Serum Lipids and Platelet Function

Hämeenlinna Metabolic Syndrome Research Program (HMS): Effects of Dietary Cold-pressed Turnip Rapeseed Oil and Milk Fat on Serum Lipids, Oxidized LDL, Arterial Elasticity and Platelet Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Kanta-Häme Central Hospital · Other Government
• Sex: Male
• Age: 31 Years – 66 Years
• Healthy volunteers: Not accepted

Summary

In this study, the effects of dietary intake of cold-pressed turnip rapeseed oil (CTPRO) and milk fat are compared in men with metabolic syndrome having already participated in HMS-02 study.

Detailed description

This open and balanced cross-over study consists of two dietary treatment phases (either Virgino (R) CTPRO or butter) for 6 to 8 weeks. They are separated from each other with an eight-week washout period. At the end of both periods and 12-hour fasting an oral glucose-fat tolerance test is carried out. Except glucose, the test consists cream (after the butter phase) and CTPRO (after the CTPRO phase). Otherwise, the subjects (n=43) are asked to maintain their normal dietary habits.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cold-pressed turnip rapeseed oil (CTPRO)	1. In the dietary period of 6 to 8 weeks: CTPRO 37 ml/day. 2. In the 5-hour oral glucose and fat tolerance test: glucose and CTPRO.
DIETARY_SUPPLEMENT	milk fat	1. In dietary period of 6 to 8 weeks: 37.5 grams of butter. 2. In the 5-hour oral glucose and fat tolerance test: glucose and cream

Timeline

• Start date: 2004-09-01
• Primary completion: 2005-04-01
• Completion: 2008-06-01
• First posted: 2010-05-07
• Last updated: 2010-05-07

Locations

4 sites across 1 country: Finland