NCT01119131

Effects of Vitamin D in Parkinson's Disease (PD)

The Effects of Vitamin D on Balance in Persons With PD

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 101 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 50 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

A trial to measure the effects of vitamin D (versus a placebo) on balance, gait, falls, strength, and cognition in persons with Parkinson's disease.

Detailed description

The proposed study is a randomized, double-blinded, placebo controlled intervention trial to measure the effects of vitamin D at (10,000IU/day) versus placebo on balance and falls in Parkinson's disease. The investigators will measure static, dynamic, and ambulatory balance, as well as strength, falls, and cognition before and after 16 weeks of therapy. Dynamic posturography will be used to measure static and ambulatory balance, a device called iMOBILITY will measure a timed up and go, and strength will be measured with the Biodex machine checking knee flexion and extension. Multiple quality of life and cognitive tests will also be performed.

Conditions

• Parkinson Disease
• Accidental Falls

Interventions

Type	Name	Description
DRUG	Vitamin D3	Vitamin D3 at 10,000 IU a day
DIETARY_SUPPLEMENT	calcium	1000mg calcium daily
OTHER	Placebo	A placebo pill with similar appearance to the vitamin D3 will be given to those in the placebo arm

Timeline

• Start date: 2011-05-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2010-05-07
• Last updated: 2016-03-07
• Results posted: 2016-03-07

Locations

1 site across 1 country: United States