NCT01112176

Effect of Heart Rate on Left Ventricular Performance

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The current study is aimed at determining the normal response to increasing heart rates. For this purpose, atrial pacing will be used to increase heart rate.

Detailed description

Participants will be patients with pacemakers and normal A-V node conduction with a possibility for right atrial pacing mode. Detailed Echo studies will be performed at baseline. Echo studies will be repeated at each pacing stage, stages defined as 10 bpm increments in paced heart rate. Each stage will last 2-3 min or as long as it takes to record the echo study. Heart rate will be increased to 85% of predicted heart rate for age or at to appearance of signs of ischemia. Hemodynamic parameters will be recorded and segmental longitudinal strain will be calculated (as well as other Echo data), for each stage.

Conditions

• Myocardial Function
• Myocardial Strain

Interventions

Type	Name	Description
PROCEDURE	Increase in paced heart rate	The pacing rate will be increased by 10 bps at every stage

Timeline

• Start date: 2010-04-01
• Primary completion: 2012-04-01
• Completion: 2012-04-01
• First posted: 2010-04-28
• Last updated: 2010-04-28

Locations

1 site across 1 country: Israel