Clinical Trials Directory

Trials / Completed

CompletedNCT01110525

A Drug-drug Interaction Study to Investigate the Effects of AZD1981 on the Metabolism and Pharmacodynamics of Oral Contraceptives

A Phase I, Double-blind, Randomised, Placebo-controlled, Two-cycle Crossover, Drug-drug Interaction Study to Investigate the Effects of AZD1981 Tablets 400 mg Twice Daily on the PK and PD of Oral Contraceptives in Healthy Female Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
28 (estimated)
Sponsor
AstraZeneca · Industry
Sex
Female
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

The primary purpose of this study is to determine whether the treatment with AZD1981 will affect the metabolism of hormones included in oral contraceptives.

Conditions

Interventions

TypeNameDescription
DRUGAZD19814X100 mg per oral, twice daily for 28 days
DRUGNeovletta 21/28Once daily with (21) or without (28) pause for bleeding.
DRUGPlacebo AZD19814X100 mg per oral, twice daily for 28 days

Timeline

Start date
2010-05-01
Primary completion
2010-10-01
Completion
2010-10-01
First posted
2010-04-26
Last updated
2010-11-18

Locations

2 sites across 1 country: Sweden

Source: ClinicalTrials.gov record NCT01110525. Inclusion in this directory is not an endorsement.