Trials / Completed
CompletedNCT01109823
Pharmacokinetic Evaluation of Fluoroquinolone Antibiotics Administered Intravenously in Intensive Care Patients With Normal Renal Function and With Renal Hyperfiltration
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 14 (actual)
- Sponsor
- University Ghent · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
At the intensive care unit (ICU) fluoroquinolone antibiotics, like levofloxacin, are frequently used for the treatment of infections. Adequate blood levels are required for a good efficacy of the antibiotic. Due to the fact that levofloxacin is almost completely eliminated renally, the blood levels for this antibiotic are strongly influenced by the renal function. Therefore, this study aims to evaluate the pharmacokinetics of levofloxacin in patients with hyperfiltration, in comparison with critically ill patients with normal renal function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | intravenous administration of levofloxacin | Intravenous administration of levofloxacin is used. |
Timeline
- Start date
- 2010-05-19
- Primary completion
- 2013-12-01
- Completion
- 2013-12-01
- First posted
- 2010-04-23
- Last updated
- 2021-06-29
Locations
2 sites across 1 country: Belgium
Source: ClinicalTrials.gov record NCT01109823. Inclusion in this directory is not an endorsement.