Clinical Trials Directory

Trials / Terminated

TerminatedNCT01108705

Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib Treatment

A Randomized, Double-blind, Multi-center Phase III Study of Brivanib Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Asian Subjects With Advanced Hepatocellular Carcinoma (HCC) Who Have Failed or Are Intolerant to Sorafenib

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
87 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether brivanib is an effective treatment for liver cancer in Asian patients who have failed or could not tolerate sorafenib therapy.

Conditions

Interventions

TypeNameDescription
DRUGBrivanibTablets, Oral, 800 mg, once daily, until disease progression or toxicity
DRUGPlaceboTablets, Oral, 0mg, once daily, until disease progression or toxicity

Timeline

Start date
2010-05-01
Primary completion
2013-10-01
Completion
2013-10-01
First posted
2010-04-22
Last updated
2015-10-12

Locations

32 sites across 4 countries: China, Singapore, South Korea, Taiwan

Source: ClinicalTrials.gov record NCT01108705. Inclusion in this directory is not an endorsement.

Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patien (NCT01108705) · Clinical Trials Directory