NCT01108289

Effect of Prophylactic Administration of Oxytocin in Uniject™ on Postpartum Hemorrhage at Home Births in Ghana

The Oxytocin Initiative: Determining the Effect of Prophylactic Administration of Oxytocin in Uniject™ by a Community Health Officer on Postpartum Hemorrhage at Home Births in Four Districts in Ghana

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,586 (actual)
• Sponsor: Johns Hopkins Bloomberg School of Public Health · Academic / Other
• Sex: Female
• Age: 15 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by a Community Health Officer (CHO) at home births in Ghana will reduce the risk of postpartum hemorrhage by 50 percent relative to home births attended by the same type of provider who does not provide a uterotonic drug.

Conditions

• Postpartum Hemorrhage

Interventions

Type	Name	Description
OTHER	Oxytocin in Uniject	10 IU Oxytocin delivered intramuscularly immediately after delivery of the baby

Timeline

• Start date: 2011-04-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2010-04-21
• Last updated: 2013-07-02

Locations

1 site across 1 country: Ghana