Trials / Completed
CompletedNCT01108250
LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean Population
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 215 (actual)
- Sponsor
- Kyungpook National University Hospital · Academic / Other
- Sex
- All
- Age
- 60 Years
- Healthy volunteers
- Accepted
Summary
This study is to investigate whether variants in the LOC387715 locus and the HtrA serine peptidase 1 (HTRA1) gene within the 10q26 locus are associated with polypoidal choroidal vasculopathy and whether they are associated with clinical patterns including angiographic phenotype in a Korean population.
Detailed description
This is a cross-sectional case-control study. One hundred Korean patients with polypoidal choroidal vasculopathy and 100 control subjects were genotyped for the LOC387715 (rs10490924) and the HTRA1 gene polymorphism (rs11200638)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | LOC387715/HTRA1 genotyping | Genomic DNA was extracted from whole blood by standard methods. Genotyping was performed using SNP Genotyping Assays. |
Timeline
- Start date
- 2010-04-01
- Primary completion
- 2010-08-01
- Completion
- 2011-08-01
- First posted
- 2010-04-21
- Last updated
- 2011-08-30
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01108250. Inclusion in this directory is not an endorsement.