NCT01107184

Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)

A Clinical Study on the Effect of Remote Ischemic Conditioning on Atrial Fibrillation and Outcome After Coronary Artery Bypass Grafting

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 191 (actual)
• Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Recent studies indicate that remote ischemic conditioning can protect the heart and other organs during cardiac surgery. The investigators aim to investigate whether such a stimulus can reduce the incidence of atrial fibrillation or other complications following coronary artery bypass surgery.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
PROCEDURE	Remote ischemic conditioning	Patients will have a automated inflator cuff placed on the upper arm during surgery. The cuff will be used to induce fore arm ischemia by inflation to 200 mmHg for 3 x 5 minutes, interspersed with 5 minutes of no-inflation and thus reperfusion.
PROCEDURE	Sham	Patients will have a automated inflator cuff placed on the upper arm during surgery which will not be inflated.

Timeline

• Start date: 2010-01-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2010-04-20
• Last updated: 2018-02-01

Locations

1 site across 1 country: Netherlands