NCT01106547

The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy

The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy: A Prospective, Double Blinded, Placebo Controlled Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 55 (estimated)
• Sponsor: Holbaek Sygehus · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effect of 125 mg methylprednisolone, given intravenously 60-90 minutes before abdominal surgery,on the postoperative rehabilitation after abdominal hysterectomy.Sodium Chloride is the placebo. The following parameters are registered: 1. Pain 3, 6 and 24 hours postoperatively and 2-7 days after surgery. 2. The postoperative use of additional analgesics. 3. Inflammatory parameters before and after surgery. 4. Time until mobilization. 5. Time until discharge.

Conditions

• Hysterectomy
• Methylprednisolone
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Methylprednisolone 125mg	Single dose 60-90 minutes preoperatively
DRUG	Sodium Chloride 2 ml	Single dose 60-90 min preoperatively

Timeline

• Start date: 2009-08-01
• Primary completion: 2011-09-01
• Completion: 2011-10-01
• First posted: 2010-04-20
• Last updated: 2011-10-13

Locations

1 site across 1 country: Denmark