NCT01104207

Transcranial Magnetic Stimulation for Tinnitus

Clinical Trial of Transcranial Magnetic Stimulation for Relief of Tinnitus

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the effectiveness of repetitive transcranial magnetic stimulation (rTMS) for reducing the loudness or severity of chronic tinnitus.

Detailed description

This is a prospective, randomized, subject and clinician/observer blind, placebo-controlled parallel-group clinical trial of rTMS involving people who experience chronic tinnitus. Eligible subjects are randomly assigned to receive either active rTMS treatment or placebo treatment to either the left or right side of the head. Subjects receive 2000 pulses of 1 Hz rTMS therapy daily on 10 consecutive work days. Outcomes are measured prior to the start of treatment and after the last therapeutic session. Follow-up evaluations are conducted 1, 2, 4, 13 and 26 weeks after the last treatment session. This design allows us to determine if rTMS reduces the severity and loudness of tinnitus, the long-term duration of relief, and whether the target for coil placement (left/right side of head) affects active rTMS efficacy.

Conditions

• Tinnitus

Interventions

Type	Name	Description
DEVICE	repetitive transcranial magnetic stimulation (rTMS)	rTMS involves application of electromagnetic pulses through a coil to the subject's scalp. Some of the electromagnetic energy is transmitted to underlying neural tissue. The goal for this study: 1 Hz rTMS will suppress neural activity responsible for tinnitus perception.
DEVICE	placebo rTMS	placebo rTMS

Timeline

• Start date: 2011-03-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2010-04-15
• Last updated: 2017-03-29
• Results posted: 2017-02-23

Locations

1 site across 1 country: United States