NCT01103206

Evaluation of a Cincalcet Suppression Test

Evaluation of a Parathyroid Hormone Suppression Test With Cinacalcet. Comparison: 1- With the Results of the Intravenous Calcium Suppression Test in Healthy Controls; 2- Between Healthy Controls and Patients With Primary Hyperparathyroidism.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to compare the results of a parathyroid hormone (PTH)suppression test using a single oral tablet of cinacalcet in two groups of subjects: 1- a group of healthy adults in whom the results of the test with cinacalcet will be compared with those of the standardized PTH suppression test with intravenous calcium loading; 2- a group of patients with proven primary hyperparathyroidism in whom the results of the test with cinacalcet will be compared with those obtained during the same test, in healthy controls.

Conditions

• Parathyroid Hormone Suppression Test With Cinacalcet

Interventions

Type	Name	Description
DRUG	cinacalcet	Intake of a single tablet of cinacalcet
DRUG	cinacalcet dose 1	PTH suppression test in primary hyperparathyroidism using cinacalcet (dose 1).
DRUG	cinacalcet dose 2	Parathyroid hormone suppression test in primary hyperparathyroidism using cinacalcet (dose 2).

Timeline

• Start date: 2010-04-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2010-04-14
• Last updated: 2026-04-16

Locations

1 site across 1 country: France