NCT01101204

The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines

Effects of High and Low Doses of Metformin, Fenofibrate and Simvastatin, Administered Together and in Sequence With Lifestyle Intervention on Lipid Profile, Glucose Metabolism, Low-grade Inflammation and Hemostasis in Patient's Blood Plasma in Type 2 Diabetic Patients With Serious Mixed Dyslipidemia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Medical University of Silesia · Academic / Other
• Sex: All
• Age: 35 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The study is planned to show whether combined hypolipemic and antidiabetic therapy with various daily dosages influence the fasting plasma glucose, insulin sensitivity and proinflammatory cytokines in diabetic and dyslipidemic subjects.

Conditions

• Diabetes
• Dyslipidemia
• Inflammation
• Cytokines

Interventions

Type	Name	Description
DRUG	Metformin 1000mg, simvastatin 10mg and fenofibrate 100mg	Patient will take three pill consisting of metformin 1000mg, simvastatin 10mg and fenofibrate 100mg.

Timeline

• Start date: 2012-07-01
• Primary completion: 2012-10-01
• Completion: 2012-12-01
• First posted: 2010-04-09
• Last updated: 2012-07-09

Locations

1 site across 1 country: Poland