NCT01100424

Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Alcon Research · Industry
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study was to investigate the association of inflammatory mediators found in the tear film during the development and following the induction of contact lens solution-induced corneal staining.

Conditions

• Corneal Staining

Interventions

Type	Name	Description
DEVICE	Opti-Free RepleniSH	Commercially available contact lens solution used for pre-soaking balafilcon A contact lenses overnight prior to lens insertion.
DEVICE	ReNu MultiPlus	Commercially available contact lens solution used for pre-soaking balafilcon A contact lenses overnight prior to lens insertion.
DEVICE	Balafilcon A	Commercially available silicone hydrogel contact lenses removed from blister pack and soaked overnight in Opti-Free Replenish, ReNu MultiPlus, or Unisol 4, then applied to the eye and worn for 2 hours.
OTHER	Unisol 4	Commercially available non preserved sterile saline solution used for pre-soaking balafilcon A contact lenses overnight prior to lens insertion.

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-09-01
• Completion: 2010-09-01
• First posted: 2010-04-09
• Last updated: 2012-10-23

Locations

1 site across 1 country: United States