Trials / Completed
CompletedNCT01097902
Study of Experimental Models of Pain and Inflammation.
Experimental Inflammatory and Micro-incisional Pain Model Analysis by Gene Expression and Interstitial Fluid Proteomics of Skin Tissue
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Martin Angst · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The experimental pain model studied in this proposal show characteristics of an inflamed wound with a pro-inflammatory response. This study will help discover candidate genetic and/or proteomic pain biomarkers that could provide objective and mechanism based tests to diagnose, monitor or quantify pain. We also hope to determine the measurable effects of a known non-steroidal anti-inflammatory drug (NSAID) on biomarkers of pain and inflammation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ibuprofen | 800 mg oral one time only |
| DRUG | Placebo tablet | Placebo tablet oral one time only |
Timeline
- Start date
- 2010-02-01
- Primary completion
- 2010-09-01
- Completion
- 2010-09-01
- First posted
- 2010-04-02
- Last updated
- 2013-06-19
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01097902. Inclusion in this directory is not an endorsement.