Trials / Completed
CompletedNCT01095900
Comparison of Botulinum Toxin and Sphincterotomy in the Treatment of Chronic Anal Fissure
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Theodor Bilharz Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
Intra-sphincteric injection of botulinum toxin seems to be a reliable option causing temporary alleviation of sphincter spasm and allowing the fissure to heal. study is to compare the outcome of surgical sphincterotomy and botulinum toxin injection treatments in patients with uncomplicated chronic anal fissure.
Detailed description
consecutive patients with uncomplicated chronic anal fissure who had failed conservative treatment were randomized to receive either intra-sphincteric injection of botulinum toxin (BT) or lateral internal sphincterotomy (LIS). Postoperative pain relief, healing of fissure, continence scores and fissure relapse during 18 weeks of follow up was the outcomes assessed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | conservative lateral internal sphincterotomy | |
| PROCEDURE | Intra-sphincteric Botulinum-toxin injection |
Timeline
- First posted
- 2010-03-30
- Last updated
- 2010-03-30
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT01095900. Inclusion in this directory is not an endorsement.