NCT01093339

To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure

To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure, and if This Effect is Mediated in Gastroesophageal Reflux Disease (GERD)Patients by Altering Appetite Regulation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Southern Arizona VA Health Care System · Federal
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.

Detailed description

To determine if increased esophageal acid exposure is mediated by altering appetite regulation. To assess if there is any relationship between sleep deprivation and the serum level of TNF-alfa (a protein that can be elevated in inflammation).

Conditions

• Gastroesophageal Disease

Timeline

• Start date: 2006-08-01
• Primary completion: 2010-03-01
• Completion: 2010-03-01
• First posted: 2010-03-25
• Last updated: 2010-08-19

Locations

1 site across 1 country: United States