NCT01091649

Study in Healthy Adults to Evaluate the Bioavailability of Two Test Tablet Formulations of ABT-450

An Open-label, Randomized, Crossover Study to Evaluate the Bioavailability of Two Candidate Tablet Formulations of ABT-450 With Reference to the Hard Gelatin Capsule Formulation

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Abbott · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to assess the relative bioavailability of two test tablet formulations of ABT-450 as compared to the ABT-450 hard gelatin capsule formulation as a reference.

Detailed description

This is a two part study. Part 1 is a single dose, three period, complete crossover study in approximately 21 subjects. Part 2 is a single dose, two period, complete crossover study in approximately 20 subjects.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	ABT-450	Low dose ABT-450 / ritonavir see Arm Description for more information
DRUG	ritonavir	ritonavir see Arm Description for more information
DRUG	ABT-450	High dose ABT-450 / ritonavir See Arm Description for more information

Timeline

• Start date: 2010-02-01
• Primary completion: 2010-04-01
• Completion: 2010-04-01
• First posted: 2010-03-24
• Last updated: 2010-12-21

Locations

1 site across 1 country: United States