NCT01088087

Effect of Colostrum on Gut Permeability and Endotoxin Level in Chronic Alcoholic Disease

Effect of Colostrum Administration on Improving Gut Permeability and Serum Endotoxin Level in Chronic Alcohol Drinkers With Hepatic Dysfunction

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 34 (estimated)
• Sponsor: Gangnam Severance Hospital · Academic / Other
• Sex: Male
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

Chronic alcohol ingestion is related with leaky gut syndrome. Colostrum is well-studied that it has a effect of decreasing the degree of leaky gut syndrome. So the investigators are planning to find out whether Colostrum has a effect of decreasing the degree of leaky gut syndrome.

Detailed description

We randomly sort the participant as placebo group and colostrum group. Each group consists of 17 people. and the duration of our study for one participant is 3 weeks. (Participant takes colostrum for 3 weeks.) When a person gets leaky gut syndrome, his or her endotoxin and lactulose/mannitol ratio (L/M ratio, in urine) can elevate. So We will compare the value of those two parameters and LFT. etc. after the administration of colostrum or placebo.

Conditions

• Leaky Gut Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	colostrum	colostrum, 2g, 2 times a day, for 3 weeks

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-09-01
• Completion: 2010-12-01
• First posted: 2010-03-17
• Last updated: 2010-03-17

Locations

1 site across 1 country: South Korea