NCT01076673

Effect of Autologous Peripheral Blood Stem Cell Treatment on Articular Cartilage Regeneration

Articular Cartilage Regeneration With Autologous Peripheral Blood Stem Cells Versus Hyaluronic Acid: A Randomized, Controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Kuala Lumpur Sports Medicine Centre · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to compare histologic and MRI evaluation of articular cartilage regeneration in patients with chondral lesions treated by arthroscopic subchondral drilling followed by postoperative intra-articular injections of hyaluronic acid (HA) with and without peripheral blood stem cells (PBSC)

Detailed description

The purpose of this study was to compare histologic and magnetic resonance imaging (MRI) evaluation of articular cartilage regeneration in patients with chondral lesions treated by arthroscopic subchondral drilling followed by postoperative intra-articular injections of hyaluronic acid (HA) with and without peripheral blood stem cells (PBSC)

Conditions

• Articular Cartilage Disorder of Knee

Interventions

Type	Name	Description
BIOLOGICAL	Peripheral blood stem cells and hyaluronic acid injections	Peripheral blood stem cells and hyaluronic acid injections
DRUG	Hyaluronic Acid	Hyaluronic acid injections

Timeline

• Start date: 2009-10-01
• Primary completion: 2012-05-01
• Completion: 2012-05-01
• First posted: 2010-02-26
• Last updated: 2015-03-17

Locations

1 site across 1 country: Malaysia