Clinical Trials Directory

Trials / Completed

CompletedNCT01076309

Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin

Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Systemic Sympathetic Alfa-1-a-antagonist Medication (Tamsulosin)

Status
Completed
Phase
Study type
Observational
Enrollment
60 (actual)
Sponsor
Frederiksberg University Hospital · Academic / Other
Sex
Male
Age
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether corneal endothelium cell loss during cataract surgery is higher in patients taking Tamsulosin.

Detailed description

Cataract surgery in patients taking Tamsulosin is regarded as more challenging for the surgeon because Intraoperative Floppy Iris Syndrome (IFIS) might occur. However, the question is whether this has any practical implication for the outcomes of surgery. In this study we investigate whether cornea is damage during surgery on Tamsulosin patient. In an observational study 30 cataract patients taking Tamsulosin is compared to 30 patients not taking Tamsulosin, but otherwise similar. Number of patients is based on power calculation. Cornea is examined by specular microscopy.

Conditions

Timeline

Start date
2009-06-01
Primary completion
2010-09-01
Completion
2010-09-01
First posted
2010-02-26
Last updated
2011-07-21

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT01076309. Inclusion in this directory is not an endorsement.