NCT01075932

Effects of Docosahexaenoic Acid (DHA)-Rich Fish Oil on Cerebral Haemodynamics

The Cognitive And Cerebral Hemodynamic Effects Of DHA-Rich Fish Oil: A Dose-Ranging Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: Northumbria University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

DHA has previously been shown to increase regional cerebral blood flow response to tactile stimulation in aged monkeys; modulation of cerebral blood flow in humans has yet to be demonstrated. Given that the brain relies on a constant supply of blood-borne metabolic substrates (e.g. glucose, oxygen), increasing regional cerebral blood flow may also have an impact on cognitive function. The current study aims to investigate the effects of two doses of DHA-rich fish oil on task-related cerebral hemodynamic response and cognitive performance in healthy adults.

Conditions

• Cerebral Blood Flow
• Cognitive Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	DHA-rich fish oil	Either 1 g or 2 g DHA-rich fish oil taken daily for 12 weeks. Participants in the 1 g group will also consume 1 g olive oil placebo capsules per day to maintain double blind.
DIETARY_SUPPLEMENT	Placebo	2 g placebo (olive oil) taken daily for 12 weeks

Timeline

• Start date: 2009-04-01
• Primary completion: 2009-05-01
• Completion: 2009-08-01
• First posted: 2010-02-25
• Last updated: 2010-02-25

Locations

1 site across 1 country: United Kingdom