Trials / Withdrawn
WithdrawnNCT01075776
The Effects of C-type Natriuretic Peptide on Human Forearm Blood Vessels
The Effects of C-type Natriuretic Peptide on Endothelial Function Following Ischaemia-Reperfusion in the Human Forearm
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Queen Mary University of London · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
To determine the effects of whether increasing CNP concentrations slightly above normal will improve the functioning of blood vessels after the interruption in the flow of blood. In this study we are looking at the function of the blood vessels of the forearm, as a substitute for those in the heart
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | C-type natriuretic peptide (CNP) | 360 pmol/min for 15 minutes intra-arterially |
| DRUG | Saline | Sodium Chloride 0.9% intra-arterially 0.5ml/min |
| DRUG | Acetylcholine | 2 stepped infusions for a total 9min per limb, totalling 1.05micromoles per limb |
Timeline
- Start date
- 2020-01-01
- Primary completion
- 2022-01-01
- Completion
- 2023-01-01
- First posted
- 2010-02-25
- Last updated
- 2020-05-05
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT01075776. Inclusion in this directory is not an endorsement.