NCT01075061

Study of a Large Family With Congenital Mirror Movements : From Underlying Pathophysiology to Culprit Gene Identification PROJET " MOMIC "

Study of a Large Family With Congenital Mirror Movements : From Underlying Pathophysiology to Culprit Gene Identification : MOMIC

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Institut National de la Santé Et de la Recherche Médicale, France · Other Government
• Sex: All
• Age: 11 Years – 82 Years
• Healthy volunteers: Accepted

Summary

Mirror movements are involuntary, symmetrical and simultaneous movements occurring on one side of the body that accompany controlateral voluntary movements. Congenital mirror movements (CMM) are characterized by childhood onset and the absence of additional manifestations. The aim of this study is to unravel the pathophysiology of the CMM that remains poorly elucidated. The combination of imaging studies and neurophysiological studies using transcranial magnetic stimulation in a homogeneous and relatively large group of patient is likely to allow us to better understand the underlying pathophysiology of the disorder. Using a linkage analysis approach we will try to identify a locus associated with CMM and related candidate genes.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	healthy volunteers	morphological and functional brain MRI; transcranial magnetic stimulation
OTHER	Kallmann	morphological and functional brain MRI; transcranial magnetic stimulation
OTHER	Congenital Mirror Movement	morphological and functional brain MRI; transcranial magnetic stimulation

Timeline

• Start date: 2010-02-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2010-02-24
• Last updated: 2025-08-27

Locations

1 site across 1 country: France