Clinical Trials Directory

Trials / Completed

CompletedNCT01073384

A Dose Ranging Study of Delayed Release Beclomethasone for Prevention of Acute Enteritis in Patients With Rectal Cancer

A Phase 1/2 Study to Evaluate Escalating Doses of SGX201 [Delayed Release Oral Beclomethasone Dipropionate (BDP)] for Prevention of Signs and Symptoms of Acute Enteritis in Patients With Rectal Cancer Treated With Combined Chemotherapy and Radiation Therapy

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Soligenix · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and preliminary efficacy of four doses of SGX201 in subjects with rectal cancer treated with concurrent radiation and chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGSGX201 (delayed release beclomethasone 17,21-dipropionate)Delayed release beclomethasone 17,21-dipropionate before the first administration of radiation therapy continuing for 7 days after the end of radiation therapy.

Timeline

Start date
2009-12-01
Primary completion
2012-01-01
Completion
2012-11-01
First posted
2010-02-23
Last updated
2012-12-17

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01073384. Inclusion in this directory is not an endorsement.