NCT01073371

Anesthetic Efficacy of Liposomal Prilocaine in Maxillary Infiltration Anesthesia

Local Anesthetics New Formulations: From Development to Clinical Tests

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: University of Campinas, Brazil · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This blinded randomized, crossover, three period study aim to evaluate the anesthetic efficacy of liposome-encapsulated 3% prilocaine compared to 3% plain prilocaine and 3% prilocaine with 0,03IU/mL felypressin, after 1.8mL infiltration in the buccal sulcus of the maxillary right canine, in 32 volunteers.

Conditions

• Dental Anesthesia Efficacy

Interventions

Type	Name	Description
DRUG	Prilocaine	1.8mL infiltration of liposome-encapsulated 3% prilocaine, 3% plain prilocaine or 3% prilocaine with 0,03IU/mL felypressin in the buccal sulcus of the maxillary right canine

Timeline

• Start date: 2008-07-01
• Primary completion: 2009-08-01
• Completion: 2009-11-01
• First posted: 2010-02-23
• Last updated: 2010-02-23

Locations

1 site across 1 country: Brazil