NCT01073241

Transurethral Ventral Wall of Urethra-preserving Enucleation of Prostate

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Southwest Hospital, China · Academic / Other
• Sex: Male
• Age: 45 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

In this study, the investigators designed a randomized and double-blind prospective trial to evaluate the efficiency and safety of the investigators new approach-transurethral ventral wall of urethra-preserving enucleation of prostate in comparison with TURP for the hyperplasia weighing more than 45 g.

Detailed description

Although in recent dozen of years, laser operation and other safer minimally invasive surgeries have been well-developed, transurethral resection of the prostate (TURP) is still the gold standard for the surgical treatment of benign prostatic hyperplasia, despite of its various complications, and not suitable for the hyperplasia over 80 g which should be resected under open surgery. In this study, we design a randomized and double-blind prospective trial to evaluate the efficiency and safety of our new approach-transurethral ventral wall of urethra-preserving enucleation of prostate in comparison with TURP for the hyperplasia weighing more than 45 g.Urodynamic examination \[maximum flow rate (QMax), detrusor pressure, and so on\], transrectal color Doppler ultrasonography for the prostate, blood routine, blood electrolyte, prostate specific antigen (PSA), International Prostate Symptom Score (IPSS), the quality of life (Qol), blood loss during operation, and the weight of resected prostate were studied before and after the operation.

Conditions

• Benign Prostatic Hyperplasia

Interventions

Type	Name	Description
PROCEDURE	transurethral ventral wall of urethra-preserving enucleation of prostate	The patients' ventral wall of the prostate urethra was preserved and enucleation of prostate was performed for the left hyperplasia in the envelop.
PROCEDURE	transurethral prostatic resection	The patients' prostate was resected with the conventional Nesbit TURP

Timeline

• Start date: 2010-03-01
• Primary completion: 2012-02-01
• Completion: 2012-02-01
• First posted: 2010-02-23
• Last updated: 2010-03-15

Locations

1 site across 1 country: China