NCT01069874

Trial of Vitamin D Supplementation for the Prevention of Influenza and Other Respiratory Infections (ViDiFlu)

Cluster-randomised, Double-Blind, Placebo-Controlled Trial of Vitamin D Supplementation for the Prevention of Influenza and Other Respiratory Infections in Sheltered Accommodation (ViDiFlu)

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: Barts & The London NHS Trust · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Accepted

Summary

Purpose: The study null hypothesis is that vitamin D supplementation will not influence time to acute respiratory tract infection in sheltered accommodation residents.

Detailed description

The study population will comprise sheltered accommodation residents and staff fulfilling eligibility criteria. Half of the sheltered accommodation schemes will be randomly allocated to 2-monthly oral bolus vitamin D supplementation (Vigantol oil) over a period of one year, and half to placebo. Participants will be followed for one year.

Conditions

• Respiratory Tract Infections
• Influenza

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cholecalciferol (Vitamin D/Vigantol oil)	Cholecalciferol will be administered as 2-monthly oral bolus doses of Vigantol oil over a period of one year
DIETARY_SUPPLEMENT	Miglyol oil	Miglyol oil will be administered as 2-monthly oral bolus doses of Miglyol oil over a period of one year

Timeline

• Start date: 2010-03-01
• Primary completion: 2013-04-01
• Completion: 2013-04-01
• First posted: 2010-02-17
• Last updated: 2014-02-04

Locations

2 sites across 1 country: United Kingdom