NCT01068405

Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo

Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo - Assessment of Structural and Clinical Action of Magnetic Resonance Imaging

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: All
• Age: 40 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis. The investigators purpose to measure the efficacy of methotrexate on digital arthritis. In this aim, two groups were compared. The first group receive 10mg/week of methotrexate administered in one shot (every Monday for example)during 12 months. The second group receive 10mg/week of placebo according to the same procedure

Conditions

• Polyarthritis

Interventions

Type	Name	Description
DRUG	Methotrexate	Methotrexate: 10mg/week administered in one time, the same day each week (every monday for example)during 12 months
DRUG	Placebo	Placebo:10mg/week administered in one time, the same day each week (every monday for example)during 12 months

Timeline

• Start date: 2010-03-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2010-02-15
• Last updated: 2011-12-09

Locations

1 site across 1 country: France