NCT01067898

A Study on Oral Vitamin D Megadoses

A Randomized, Double-blind, Placebo-controlled Study on Oral Vitamin D Megadoses - 100 000 or 200 000 IU Vitamin D3 Every Three Months

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: Female
• Age: 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if infrequent administration of oral vitamin D megadoses is effective treatment to maintain serum 25-hydroxyvitamin D(3) above target levels of 50-75 nmol/L. The investigators hypothesize that 100 000 IU or at least 200 000 IU vitamin D3 in every three months would be effective and safe treatment to achieve the target levels.

Conditions

• Hypovitaminosis D

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	vitamin D3 (cholecalciferol)	vitamin D3 (cholecalciferol) oil 20 000 IU/ml, oral dose of 200 000 IU or 100 000 IU (10ml or 5ml) every three months for one year.
OTHER	olive oil	10 ml (placebo group) or 5 ml (100 000 IU vitamin D3 group) oil per os every three months for one year
DIETARY_SUPPLEMENT	calcium carbonate	1000 mg calcium per os every day for one year

Timeline

• Start date: 2010-02-01
• Primary completion: 2011-05-01
• Completion: 2011-05-01
• First posted: 2010-02-12
• Last updated: 2012-03-27

Locations

1 site across 1 country: Finland