Clinical Trials Directory

Trials / Terminated

TerminatedNCT01065077

BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

A Placebo Controlled, Randomized, Double-Blind, Fixed-dose, Multicenter, Phase IIb Study to Investigate the Efficacy and Tolerability of BAY58-2667 (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A placebo controlled, double-blind and randomized study to assess different doses of a new drug (BAY58-2667) given intravenously, to evaluate if it is safe and can help to improve the well-being of patients with acute decompensated heart failure.

Conditions

Interventions

TypeNameDescription
DRUGCinaciguat (BAY58-2667)Infusion of 150 µg/h during 48h
DRUGCinaciguat (BAY58-2667)Infusion of 100 µg/h during 48h
DRUGCinaciguat (BAY58-2667)Infusion of 50 µg/h during 48h
DRUGPlaceboInfusion of placebo during 48h

Timeline

Start date
2010-03-01
Primary completion
2011-01-01
Completion
2011-02-01
First posted
2010-02-09
Last updated
2015-10-08

Locations

59 sites across 17 countries: United States, Austria, Croatia, Finland, Germany, Israel, Italy, Japan, Poland, Romania, Russia, Serbia, Slovakia, Slovenia, Sweden, Switzerland, Thailand

Source: ClinicalTrials.gov record NCT01065077. Inclusion in this directory is not an endorsement.