Clinical Trials Directory

Trials / Unknown

UnknownNCT01064557

"AIDA" Protocol (LAP 0493)

Guideline for the Treatment of Newly Diagnosed Patients Eith Acutypromyelocytic Leukemia, Aged > 12 Months (1 Year) and <75 Years, Using All-trans Retinoic Acid in Combination With Idarubicin

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
1,068 (estimated)
Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto · Academic / Other
Sex
All
Age
1 Year – 75 Years
Healthy volunteers
Not accepted

Summary

The main purposes of the AIDA protocol are to test the role of intermittent maintenance therapy with ATRA, standard maintenance chemotherapy with methotrexate and 6-mercaptopurine of both in PCR negative patients at the end of the consolidation phase and to evaluate the role of allogeneic or autologous bone marrow transplantation in PCR positive patients at the end of the consolidation phase.

Conditions

Interventions

TypeNameDescription
DRUGall-trans retinoic acid (ATRA)

Timeline

Start date
1993-10-01
Primary completion
2020-12-01
Completion
2020-12-01
First posted
2010-02-08
Last updated
2020-10-14

Locations

80 sites across 5 countries: Belgium, Germany, Italy, Netherlands, Turkey (Türkiye)

Source: ClinicalTrials.gov record NCT01064557. Inclusion in this directory is not an endorsement.