NCT01062906

Intravenous Lidocaine for Laparoscopic Cholecystectomy

The Effect of Intravenous Lidocaine on Short-term Outcomes After Laparoscopic Cholecystectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Intravenous lidocaine has been shown to have analgesic, antinflammatory, antihyperalgesic, antithrombotics and neuroprotective properties. In a previous study conducted in patients undergoing laparoscopic cholecystectomy under general anesthesia with desflurane and fentanyl, intraoperative i.v. infusion of lidocaine spared opioids consumption in the recovery room by 30%. The purpose of this study was to determine if an i.v. infusion of lidocaine without intraoperative opioids would reduce the amount of fentanyl to the same extent and opioids-related side effects.

Conditions

• Postoperative Pain
• Opioid Consumption

Interventions

Type	Name	Description
DRUG	Lidocaine	1.5 mg/Kg as bolus and a continuous infusion of 2mg/Kg/hr until the end of surgery (closure of the skin)
DRUG	Fentanyl	Fentanyl 3 mcg/Kg as bolus at the induction and a continuous infusion of normal saline (NaCl 0.9%) until the end of surgery (skin closure)

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-03-01
• Completion: 2010-03-01
• First posted: 2010-02-04
• Last updated: 2011-01-13

Locations

1 site across 1 country: Canada