NCT01061489

Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment

Computer-based Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment (MCI) and Mild Alzheimer's Disease (AD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: University of Konstanz · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

Age-related cognitive decline is unavoidable. However, recent results of neuroplasticity-based research show that neuroplasticity-based training and physical activity might have the potential to decelerate or even reverse effects of aging and age-related cognitive impairments. Little is known whether these results also apply to pathological processes of aging such as mild cognitive impairment (MCI) and dementia. This multi-center study aims at investigating efficiency and feasibility of a neuroplasticity-based auditory discrimination training and a physical fitness training for patients suffering from mild cognitive impairment or mild Alzheimer's disease (Mini Mental State Examination, MMSE \> 19). Evaluation will include neuropsychological testing, electroencephalography (EEG) and magnetic resonance imaging (MRI) measurements as well as blood and liquor analyses.

Conditions

• Mild Cognitive Impairment (MCI)
• Mild Alzheimer's Disease

Interventions

Type	Name	Description
OTHER	auditory discrimination training	10-week neuroplasticity-based training (5 days/week, 1 hour each, PC-based), training at home
OTHER	physical movement training	10-week training, small groups (2 days/week, 1 hour each) plus homework (3 days/week)

Timeline

• Start date: 2009-08-01
• Primary completion: 2013-03-01
• Completion: 2013-03-01
• First posted: 2010-02-03
• Last updated: 2016-07-14

Locations

2 sites across 1 country: Germany