NCT01059370

Autonomic Dysreflexia in Spinal Cord Injury

Autonom Dysrefleksi Ved Rygmarvsskade

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Autonomic dysreflexia in high spinal cord-injured can be initiated by a full bladder or bowel, or when trying to empty either. This randomised study aims at evaluating whether irrigation procedure or digital stimulation or evacuation of the rectum is less provocative of autonomic dysreflexia. Participants have their bowels emptied on different days, in the morning fasting. Bladder filling with sterile saline water is evaluated on a third day as a control.

Conditions

• Autonomic Dysfunction
• Spinal Cord Injured

Interventions

Type	Name	Description
PROCEDURE	bowel emptying	Bowel is emptied using Peristeen® irrigation system one day, by digital stimulation another trial day or filling the bladder with saline water on a third trial day. BP is measured by Finometer Pro®, respiration frequency by BIOPACK and skin conductivity measured by Biopack and nor-epinephrine and epinephrine are measured in plasma three times during each examination.

Timeline

• Start date: 2009-12-01
• Primary completion: 2011-11-01
• Completion: 2012-03-01
• First posted: 2010-01-29
• Last updated: 2012-10-16

Locations

1 site across 1 country: Denmark