Clinical Trials Directory

Trials / Completed

CompletedNCT01058915

Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Plaque Composition in Patients With ST-Segment Elevation Myocardial Infarction (MI)

Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Plaque Composition Assessed by Virtual Histology in Patients With ST-Segment Elevation Acute Myocardial Infarction (VIRHISTAMI)

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
87 (actual)
Sponsor
Odense University Hospital · Academic / Other
Sex
All
Age
18 Years – 81 Years
Healthy volunteers
Not accepted

Summary

In patients with ST-segment elevation acute myocardial infarction (STEMI) increased LDL-cholesterol reduction (rosuvastatin 40 mg) will provide incremental plaque stabilization (changes in plaque composition) and plaque regression over 12 months beyond the benefit of moderate LDL-cholesterol reduction (rosuvastatin 5 mg) (assessed by IVUS and VH).

Conditions

Interventions

TypeNameDescription
DRUGRosuvastatin 5mgRosuvastatin 5mg/day
DRUGRosuvastatin 40mgRosuvastatin 40mg/day

Timeline

Start date
2007-11-01
Primary completion
2009-06-01
Completion
2009-06-01
First posted
2010-01-29
Last updated
2010-01-29

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT01058915. Inclusion in this directory is not an endorsement.