Clinical Trials Directory

Trials / Completed

CompletedNCT01058174

Liver Transplant European Study Into the Prevention of Fungal Infection

Randomized, Open Label, Non-inferiority Study of Micafungin Versus Standard Care for the Prevention of Invasive Fungal Disease in High Risk Liver Transplant Recipients

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
350 (actual)
Sponsor
Astellas Pharma Inc · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Prevention of invasive fungal infection in high risk patients following liver transplant.

Detailed description

After receiving liver transplant, subjects will be randomized to one of the two treatment arms. Study drugs will be administered for a period of 21 days, or until hospital discharge, whichever occurs first. Additionally, mortality data will be collected at the Long-term Follow-up.

Conditions

Interventions

TypeNameDescription
DRUGmicafunginintravenous infusion
DRUGfluconazoleintravenous infusion
DRUGliposomal amphotericin Bintravenous infusion
DRUGcaspofunginintravenous infusion

Timeline

Start date
2009-12-15
Primary completion
2012-05-03
Completion
2012-05-03
First posted
2010-01-28
Last updated
2024-11-18

Locations

36 sites across 14 countries: Austria, Belgium, France, Germany, Hungary, Ireland, Italy, Portugal, Romania, Russia, Saudi Arabia, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT01058174. Inclusion in this directory is not an endorsement.