NCT01056874

Effect Of Maraviroc On The Pharmacokinetics Of Digoxin

Open-Label, Fixed Sequence, Crossover Study To Estimate The Effect Of Multiple Dose Maraviroc On Single Dose Digoxin Pharmacokinetics In Healthy Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: ViiV Healthcare · Industry
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This is an open labelled study to estimate the effect of maraviroc on the pharmacokinetics of digoxin, a probe for p-glycoprotein.

Conditions

• Healthy
• HIV Infections

Interventions

Type	Name	Description
DRUG	Digoxin	Oral Digoxin 0.25 mg single dose
DRUG	Digoxin	Oral Digoxin 0.25 mg single dose on Day 5
DRUG	Maraviroc	Oral Maraviroc 300 mg twice daily for 6 days

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-04-01
• Completion: 2010-04-01
• First posted: 2010-01-26
• Last updated: 2011-04-07

Locations

1 site across 1 country: Singapore