NCT01055093

Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: German Diabetes Center · Academic / Other
• Sex: All
• Age: 18 Years – 69 Years
• Healthy volunteers: Accepted

Summary

The aim of the prospective observational GDC-Study in patients with newly diagnosed diabetes mellitus aged 18-69 years at inclusion into the study is to characterize in detail the clinical, metabolical and immunological phenotype and monitor the progression of the disease and to compare the phenotype to glucose tolerant humans of similar age, body mass and sex distribution.

Detailed description

In detail, the following questions will be answered: 1. Are there different phenotypes with respect to insulin secretion, insulin sensitivity, micro- and macrovascular status and diabetic neuropathy at time of diagnosis? 2. Which factors modify the progression of the disease (Nutrition, subclinical inflammation, energy metabolism and physical activity)? 3. Can we identify subgroups at baseline with different progression of the disease? Patients are thoroughly examined at baseline and after 2, 5, and 10 years with annual telephone contacts in between.

Conditions

• Diabetes Mellitus, Type 1
• Diabetes Mellitus, Type 2

Timeline

• Start date: 2005-09-01
• Primary completion: 2030-09-01
• Completion: 2040-09-01
• First posted: 2010-01-25
• Last updated: 2025-07-16

Locations

1 site across 1 country: Germany