NCT01054547

Topical Formulations of Liposomal Local Anesthetics

Local Anesthetic Activity of Liposomal Formulations in Dentistry

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: University of Campinas, Brazil · Academic / Other
• Sex: All
• Age: 18 Years – 43 Years
• Healthy volunteers: Accepted

Summary

This blinded cross-over study aim to evaluate the efficacy of topical liposome-encapsulated ropivacaine formulations.

Detailed description

This blinded cross-over study aim to evaluate the efficacy of topical liposome-encapsulated 1 and 2% ropivacaine gel formulations.

Conditions

• Administration, Topical Drug
• Administration, Topical
• Anesthetic Drugs

Interventions

Type	Name	Description
DRUG	Ropivacaine	100 mg of the following formulations: Liposome-encapsulated 1 and 2% ropivacaine gel, liposome placebo gel and 2.5% lidocaine and 2.5% prilocaine cream were applied once during 5 minutes.
DRUG	Ropivacaine	100 mg of the following formulations: Liposome-encapsulated 1 and 2% ropivacaine gel, liposome placebo gel and 20% benzocaine gel were applied once during 30 minutes.

Timeline

• Start date: 2006-09-01
• Primary completion: 2006-12-01
• Completion: 2007-04-01
• First posted: 2010-01-22
• Last updated: 2010-01-22

Locations

1 site across 1 country: Brazil